Mosby's 2014 Nursing Drug Reference (100 page)
Read Mosby's 2014 Nursing Drug Reference Online
Authors: Linda Skidmore-Roth
Canada only Side effects:
italics
= common;
bold
= life-threatening 
Nurse Alert
(klin-da-mye′sin)
Cleocin, Cleocin-T, Clindacin-P, Clindagel, ClindaMax, Clindasol
, Clinda-T, Clindesse, Clindets, Dalacin, Evoclin
Func. class.:
topical anti-infective
Chem. class.:
lincosamide derivative
Antibacterial activity results from inhibition of protein synthesis; bacteriostatic
For the treatment of acne vulgaris; treatment of bacterial vaginosis and anaerobic bacteria
Hypersensitivity to this product or lincomycin, history of antibiotic-associated colitis or ulcerative colitis
Precautions:
Breastfeeding, children younger than 12 yr
Calculator
• Adult/adolescent:
TOP
(gel, lotion, solution) Apply a thin film of 1% to affected areas bid
• Adult/adolescent/child ≥12 yr:
TOP (foam)
Apply 1% topical foam to affected areas once daily. If there is no improvement after 6-8 weeks, or if the condition worsens, discontinue treatment
• TOP
(medicated pledgets) Use a pledget to apply a thin film to the affected area bid; more than one pledget may be used, but each pledget should be used only once and then discarded
•
Intravaginal cream
One applicatorful (100 mg clindamycin/5 g cream) intravaginally, preferably at bedtime, for 3 or 7 consecutive days in nonpregnant women and for 7 consecutive days in pregnant women. Clindesse is administered as a single dose at any time of the day
•
Intravaginal ovules/suppositories
As an alternative to first-line therapies, the CDC recommends one ovule (100 mg clindamycin) inserted intravaginally at bedtime for 3 days
Available forms:
Topical gel, foam, lotion, pledget, solution 1%; vaginal cream 2%, vaginal suppositories 100 mg
•
Improvement occurs after 6 wk but can require 8-12 wk
•
Topical skin products are not for intravaginal therapy and are for external use only; do not use skin products near the eyes, nose, or mouth
•
Wash hands before and after use. Wash affected area and gently pat dry
•
Shake well before use (Lotion). Apply a thin film to the cleansed affected area. Massage gently into affected areas
•
Do not dispense foam directly onto hands or face; the warmth of the skin will cause the foam to melt. Instead, dispense desired amount directly into the cap or onto a cool surface. Make sure enough foam is dispensed to cover the affected area(s). If the can feels warm or the foam seems runny, run the can under cold water. To apply, pick up small amounts of the foam with the fingertips and gently massage into the affected areas until the foam disappears
•
Shake well before use. Apply a thin film to the cleansed affected area. Massage gently into affected areas; if using a solution-soaked pledget, patient may use more than 1 pledget per application as needed to treat affected areas, but each pledget should be used only once and then discarded
•
Only use dosage formulations specified for intravaginal use. Intravaginal dosage forms are not for topical therapy; do not ingest
•
Unwrap vaginal ovule (suppository) before insertion; use applicator(s) supplied by the manufacturer
•
Use applicator(s) supplied by the manufacturer
GU:
Colitis, diarrhea, overgrowth, vaginitis, vaginal moniliasis, UTI
INTEG:
Redness, burning, dermatitis, rash, pruritus
Decrease:
clindamycin effect—erythromycin
Increase:
effect of—neuromuscular blockers
Increase:
LFTs
Allergic reaction:
Assess for hypersensitivity, product may need to be discontinued
•
Contact prescriber immediately if severe diarrhea, stomach cramps/pain, or bloody stools occur
Infection:
Assess for number of lesions, severity in acne, itching in vaginosis
•
Decreased lesions in acne, infection in vaginosis
•
Improvement occurs after 6 wk but can require 8-12 wk
•
Topical skin products are not for intravaginal therapy and are for external use only; do not use skin products near the eyes, nose, or mouth
•
Wash hands before and after use. Wash affected area and gently pat dry
•
Shake well before use.
Lotion
Apply a thin film to the cleansed affected area. Massage gently into affected areas
•
Do not dispense foam directly onto hands or face; the warmth of the skin will cause the foam to melt. Instead, dispense desired amount directly into the cap or onto a cool surface. Make sure enough foam is dispensed to cover the affected area(s). If the can feels warm or the foam seems runny, run the can under cold water. To apply, pick up small amounts of the foam with the fingertips and gently massage into the affected areas until the foam disappears
•
Shake well before use. Apply a thin film to the cleansed affected area. Massage gently into affected areas; if using a solution-soaked pledget; patient may use
more than one pledget per application as needed to treat affected areas, but each pledget should be used only once and then discarded
•
Only use dosage formulations specified for intravaginal use. Intravaginal dosage forms are not for topical therapy; do not ingest
•
Unwrap vaginal ovule (suppository) before insertion; use applicator(s) supplied by the manufacturer
•
Use applicator(s) supplied by the manufacturer
Canada only Side effects:
italics
= common;
bold
= life-threatening Nurse Alert